41,819 research outputs found

    Organizing International Technological Collaboration in Subcontractor Relationships An Investigation of the Knowledge-Stickyness Problem

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    Technological knowledge is often claimed to be context-bound and sticking to local surroundings. This paper investigates how technological knowledge can be exchanged in international subcontractor relationships, using relationship-oriented organizational practices. Five hypotheses concerning such practices are tested. It is shown that the use of relationshiporiented practices varies with exports and the active development of subcontractors in product and process development activities. Moreover, international development-oriented subcontractors are more likely to use interpersonal exchange, electronic data interchange and formalized contracts than other types of subcontractors. Research implications as well as managerial implications are derived.Subcontracting, knowledge, international division og labour

    Bursts and Shocks in a Continuum Shell Model

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    We study a "burst" event, i. e. the evolution of an initial condition having support only in a finite interval of k-space, in the continuum shell model due to Parisi. We show that the continuum equation without forcing or dissipation can be explicitly written in characteristic form and that the right and left moving parts can be solved exactly. When this is supplemented by the appropriate shock condition it is possible to find the asymptotic form of the burst.Comment: 15 pages, 2 eps figures included, Latex 2e. Contribution to the proceedings of the conference: Disorder and Chaos, in honour of Giovanni Paladin, September 22-24, 1997, in Rom

    Internal computational fluid mechanics on supercomputers for aerospace propulsion systems

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    The accurate calculation of three-dimensional internal flowfields for application towards aerospace propulsion systems requires computational resources available only on supercomputers. A survey is presented of three-dimensional calculations of hypersonic, transonic, and subsonic internal flowfields conducted at the Lewis Research Center. A steady state Parabolized Navier-Stokes (PNS) solution of flow in a Mach 5.0, mixed compression inlet, a Navier-Stokes solution of flow in the vicinity of a terminal shock, and a PNS solution of flow in a diffusing S-bend with vortex generators are presented and discussed. All of these calculations were performed on either the NAS Cray-2 or the Lewis Research Center Cray XMP

    A Hyperstable Miniprotein: Additive Effects of D- and L-Ala Substitutions

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    The effects of alanine substitutions in each helical segment of the structure, and Gly to D-Ala mutations at sites where glycines have positive phi angles in the Trp-cage miniprotein are reported. The effects of the stabilizing mutation were additive, yielding a 20-residue construct (Tm = 83^o^C). Gly to L-Ala substitutions were uniformly destabilizing ([DELTA][DELTA]G~F~ > 11 kJ/mol): the preference for a D-Ala can be as large as 16 kJ/mol. Glycine to D-Ala mutations are validated as a strategy for the design of hyperstable miniprotein scaffolds suitable for stereospecific pharmacophore display
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